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Angiogenesis

Researchers from Stanford University detail new studies and findings in the area of angiogenesis

Published in Blood Weekly, April 10th, 2008

A new study, 'Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells,' is now available. "Tumor vasculature is derived from sprouting of local vessels (angiogenesis) and bone marrow (BM)-derived circulating cells (vasculogenesis). By using a model system of transplanting tumors into an irradiated normal tissue to prevent angiogenesis, we found that tumors were unable to grow in matrix metalloproteinase-9 (MMP-9) knockout mice, but tumor growth could be restored by transplantation of wild-type BM," scientists writing in the journal Cancer Cell report.

"Endothelial progenitor cells...

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