Apoptosis Therapy
Reports outline apoptosis therapy research from University of Texas, M.D. Anderson Cancer Center
Published in Blood Weekly, April 10th, 2008
Research findings, 'Reversal of chemoresistance and enhancement of apoptosis by statins through down-regulation of the NF-kappaB pathway,' are discussed in a new report. According to a study from the United States, "We recently found that simvastatin can modulate the nuclear factor-kappaB (NF-kappaB) activation pathway, but whether other statins have similar effects to those of simvastatin is unknown. Therefore, we evaluated the effect six different statins on TNF-induced NF-kappaB activation in human myeloid leukemia cells."
"We then determined whether the combination of statins and standard chemotherapeutic agents could overcome chemoresistance and augment apoptosis....
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Source: Blood Weekly (2008-04-10)
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