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Umbilical cord blood cell therapy may reduce signs and symptoms of Alzheimer's disease

Published in Blood Weekly, April 24th, 2008

Tampa, FL (March 26, 2008) — Targeted immune suppression using human umbilical cord blood cells may improve the pathology associated with Alzheimer's disease, a new study in a mouse model of this currently untreatable neurodegenerative condition reports. The study, led by researchers at the University of South Florida, is published online in the peer-reviewed journal Stem Cells and Development (www.liebertpub.com/scd).

Following a series of low-dose infusions of human umbilical cord blood cells into mice with Alzheimer's-like disease, the amount of amyloid-ß and ß-amyloid plaques -- hallmarks of Alzheimer's pathology in the brain -- was reduced 62 percent. Amyloid-ß...

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