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Gene Therapy

Research in the area of gene therapy reported from St. James University

Published in Blood Weekly, April 24th, 2008

According to recent research published in the International Journal of Hematology, "Recurrent reciprocal chromosomal translocations are frequently found in leukaemias and sarcomas as initiating events in these cancers. Mouse models of chromosomal translocations are not only important for the elucidation of the mechanism of these factors underlying the disease but are also important pre-clinical models for assessing new drug combinations, developing new rational therapeutic strategies based on new drugs and testing novel macromolecular drugs."

"We describe three technologies for creating chromosomal translocation mimics in mice, applied specifically to understand...

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