Acute Myeloid Leukemia
Data on acute myeloid leukemia detailed by P. Kirstetter and co-authors
Published in Blood Weekly, April 24th, 2008
A report, 'Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells,' is newly published data in Cancer Cell. According to a study from Monterotondo, Italy, "Mutations in the CEBPA gene are present in 7%-10% of human patients with acute myeloid leukemia (AML). However, no genetic models exist that demonstrate their etiological relevance."
"To mimic the most common mutations affecting CEBPA-that is, those leading to loss of the 42 kDa C/EBPalpha isoform (p42) while retaining the 30kDa isoform (p30)-we modified the mouse Cebpa locus to express only p30. p30 supported the formation of...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Blood Weekly
Source: Blood Weekly (2008-04-24)
More Articles from Blood Weekly
- Cord Blood
Umbilical cord blood cell therapy may reduce signs and symptoms of Alzheimer's disease - Pediatrics
Study shows lifetime effects of pediatric liver transplants - Sepsis
Acute kidney injury with sepsis -- a unique pathophysiology - Acute Leukemia
New acute leukemia research has been reported by scientists at Hokkaido University, Medical Department - Acute Myelogenous Leukemia
Investigators at Massachusetts General Hospital publish new data on acute myelogenous leukemia - Acute Myeloid Leukemia
Research results from Nihon University update knowledge of acute myeloid leukemia - More from this issue of Blood Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
