Bioengineering
New bioengineering study findings recently were published by L. Zou and co-researchers
Published in Blood Weekly, May 1st, 2008
"beta-arrestins (beta-Arrs) are known to be associated with tumor signaling pathways such as transforming growth factor-beta 1 (TGF-beta 1), P53/Murine double minute (MDM2) and NF-kappa B. To investigate the role of beta-Arr in tumor progression in vivo, we generated beta-Arr transgenic mice by subcutaneously inoculating tumor cells in them. We found that the xenograft tumor initiated earlier and grew more rapidly in beta-Arr1 transgenic mice than in both the beta-Arr2 transgenic and wild-type mice after inoculating murine liver cancer Hepa1-6 cells or lymphoma EL4 cells," scientists in Shanghai, People's Republic of China report.
"Moreover, matrix metalloproteinase 9...
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Source: Blood Weekly (2008-05-01)
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