Ischemia
Study data from Columbia University provide new insights into ischemia
Published in Blood Weekly, May 1st, 2008
According to a study from the United States, "During lung transplantation, cells in the pulmonary parenchyma are subjected to ischemia, hypothermic storage, and reperfusion injury. Platelets, whose granular contents include adhesion receptors, chemokines, and coactivating substances that activate inflammatory and coagulant cascades, likely play a critical role in the lung allograft response to ischemia and reperfusion."
"The platelet response to the pulmonary allograft, however, has never been studied. Here we report significant platelet activation immediately after lung transplantation. We performed a prospective cohort study comparing markers of platelet activation in...
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Source: Blood Weekly (2008-05-01)
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