Menopause

Research data from M. Hemelaar and colleagues update understanding of menopause

Published in Blood Weekly, May 1st, 2008

In this recently published article, scientists in Netherlands conducted a study "To study changes in the hemostatic balance during intranasal compared with oral administration of 17 beta-estradiol (E-2) and norethisterone (NET) or NET acetate in postmenopausal women. A wide range of markers of coagulation and fibrinolysis associated with coronary artery disease was tested."

"In a two-center, randomized, double-blind, comparative trial, 90 healthy postmenopausal women (aged 56.6 +/- 4.7 y) received daily continuous combined hormone therapy, either E-2/NET 175 mu g/275 mu g intranasally as a spray (n = 47) or E-2/NET acetate 1 mg/0.5 mg orally as a capsule (n = 43) for 1...

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Source: Blood Weekly (2008-05-01)

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