Acute Myeloid Leukemia

Data from S.W. Chen et al provide new insights into acute myeloid leukemia

Published in Blood Weekly, May 1st, 2008

According to recent research from Tainan, Taiwan, "Aberrant antigen expression in acute myeloid leukemia (AML) has been extensively studied in the West with limited reports from Taiwan. We carried out this retrospective study to characterize the frequency and significance of aberrant antigen expression of AML in Taiwan."

"Among 111 cases, 58 (52%) showed aberrant antigen expression, most frequently CD7 (27%) and CD56 (23%). Aberrant CD7 expression was observed in all non-AML-M3 subtypes, most frequently in AML-M7 (4/6, 67%); while CD19 expression was only observed in AML-M2 (5/36, 14%). CD56 expression was most common in AML-M5 (4/8, 50%). The relative frequency of CD19...

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Source: Blood Weekly (2008-05-01)

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