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Data on life sciences discussed by researchers at Kyushu University, Medical Institute of Bioregulation

Published in Blood Weekly, May 1st, 2008

Current study results from the report, 'Differential requirement for DOCK2 in migration of plasmacytoid dendritic cells versus myeloid dendritic cells,' have been published. According to recent research published in the journal Blood, "The migratory properties of dendritic cells (DCs) are important for their functions. Although several chemokines and their receptors have been implicated in DC migration, the downstream signaling molecules are largely unknown."

"Here we show that DOCK2, a hematopoietic cell-specific CDM family protein, is indispensable for migration of plasmacytoid DCs (pDCs), but not myeloid DCs (mDCs). Although DOCK2-deficiency did not affect...

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