Hypertension
New hypertension study findings reported from University of Mississippi Medical Center
Published in Blood Weekly, May 8th, 2008
"Previous studies suggest that activation of the CNS melanocortin system reduces appetite while increasing sympathetic activity and arterial pressure. The present study tested whether endogenous activity of the CNS melanocortin 3/4 receptors (MC3/4-R) contributes to elevated arterial pressure in the spontaneously hypertensive rat (SHR), a model of hypertension with increased sympathetic activity," scientists in the United States report.
"A cannula was placed in the lateral ventricle of male SHR and Wistar (WKY) rats for chronic intracerebroventricular (ICV) infusions (0.5 mu L/h). Mean arterial pressure (MAP) and heart rate (HR) were recorded 24 hour/d using telemetry....
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Source: Blood Weekly (2008-05-08)
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