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Obesity and Diabetes

Reports on obesity and diabetes findings from Hvidovre University provide new insights

Published in Blood Weekly, May 15th, 2008

According to recent research from Hvidovre, Denmark, "Aims/hypothesis The ability of glucagon-like peptide-1 (GLP-1) to enhance beta cell responsiveness to i.v. glucose is impaired in patients with type 2 diabetes mellitus compared with healthy individuals. We investigated whether 4 weeks of near normalisation of blood glucose (BG) improves the potentiation of glucose-stimulated insulin secretion by GLP-1."

" Nine obese patients with type 2 diabetes and inadequate glycaemic control (HbA(1c) 8.0 +/- 0.4%) were investigated before and after 4 weeks of near normalisation of BG using insulin treatment (mean diurnal blood glucose 6.4 +/- 0.3 mmol/l, HbA(1c) 6.6 +/- 0.3%)....

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