Acute Lymphocytic Leukemia

Study data from Soochow University update understanding of acute lymphocytic leukemia

Published in Blood Weekly, May 22nd, 2008

According to a study from Suzhou, People's Republic of China, "The cytogenetic anomaly der(20)del(20)(q11.2q13.3)idic(20)(p11), or idic(20q-) in short form, has been reported in 13 cases of myelodysplastic syndrome, one case of chronic myelomonocytic leukemia, and one case of acute myeloid leukemia since 2004. To our knowledge, it has not previously been described in lymphoid diseases."

"Here we report the cases of two Patients with B-cell acute lymphocytic leukemia (ALL) having a novel idic(20q-). One was a 34-year-old man with B-cell ALL whose leukemic cells at presentation had a karyotype of 45,XY,dic(9;20)(p11;q11.2); at relapse, a small marker chromosome was found...

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Source: Blood Weekly (2008-05-22)

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