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Bone Research

New findings in bone research described from Boston University, Medical Department

Published in Blood Weekly, May 22nd, 2008

"Bone disease with osteoporosis and osteomalacia are common in sickle cell disease (SCD). Some patients have vitamin D deficiency and low bone mineral density (13MID)," researchers in the United States report.

"The role of vitamin D and calcium supplementation to restore bone health in SCD has not been well studied. In 14 adults with SCD, we measured 25(OH)D (25-hydroxyvitamin D) and BMD at the femoral neck, lumbar spine, and distal third of the ulna plus radius, along with markers of bone resorption (CTx; C-terminal component of pro-collagen type 1) and bone formation (osteocalcin) before and after 12 months of vitamin D-2 and calcium carbonate treatment. Pretreatment,...

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