Gene Therapy
Scientists at INSERM detail research in gene therapy
Published in Blood Weekly, May 22nd, 2008
Fresh data on gene therapy are presented in the report 'Activation and inhibition of the erythropoietin receptor by a membrane-anchored erythropoietin.' According to a study from Paris, France, "To investigate whether expression of a membrane-anchored form of erythropoietin (MbEpo) results in self-controlled, autocrine proliferation, and differentiation of erythroid cells. This would provide a possible approach to the selective expansion of genetically corrected erythroid cells in gene-therapy protocols."
"We designed retroviral vectors encoding MbEpo or secreted erythropoietin (Epo) and enhanced green fluorescent protein. Several Epo-dependent cell lines were...
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Source: Blood Weekly (2008-05-22)
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