Wiley-Blackwell

Study identifies molecular response of cartilage to injury

Published in Blood Weekly, June 5th, 2008

It's an unfortunate fact backed by studies of former professional football and soccer players: injury to joint cartilage escalates the risk of developing of osteoarthritis (OA). However, why this occurs—the details of how joint cartilage cells respond to acute trauma and how this response leads to progressive cartilage degradation—remains open to investigation.

To shed further light on this issue of intense research interest, an international team of rheumatologists and biotechnologists conducted a microarray screening of adult human joint cartilage subjected to injury. Led by Dr. Francesco Dell'Accio, a Clinician Scientist Fellow of the Arthritis Research Campaign, the...

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Source: Blood Weekly (2008-06-05)

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