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Cardiovascular Disease

Scientists at Osaka Medical College, Department of Internal Medicine III target cardiovascular disease

Published in Blood Weekly, June 12th, 2008

Scientists discuss in 'Role of gp91phox-containing NADPH oxidase in left ventricular remodeling induced by intermittent hypoxic stress' new findings in cardiovascular disease. According to a study from Takatsuki, Japan, "Intermittent hypoxia due to sleep apnea syndrome is associated with cardiovascular diseases. However, the precise mechanisms by which intermittent hypoxic stress accelerates cardiovascular diseases are largely unclear."

"The aim of this study was to investigate the role of gp91(phox)-containing NADPH oxidase in the development of left ventricular (LV) remodeling induced by intermittent hypoxic stress in mice. Male gp91(phox)-deficient (gp91(-/-)) mice...

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