Gaucher Disease

Research on Gaucher disease reported by scientists at University of Amsterdam

Published in Blood Weekly, June 12th, 2008

"Gaucher disease type I, the most common lysosomal storage disorder, is associated with immunoglobulin abnormalities. We studied the prevalence, risk factors, pathogenesis, and effect of enzyme relation therapy (ERT) on gammopathies in an adult Gaucher disease type I cohort (N=63) and related the results to a review of the currently available literature," scientists in Netherlands report.

"Polyclonal gammopathies and monoclonal gammopathy of undetermined significance (MGUS) in our adult GD I cohort were found in 41% and 19% of patients. These results are similar to the data from the literature and correspond to the increased risk of multiple myeloma (MM) that has been...

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Source: Blood Weekly (2008-06-12)

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