Published in Blood Weekly, June 19th, 2008
"Design and Methods The factor VIII gene (F8) was analyzed in 1296 unrelated patients with hemophilia A using screening methods for intron 22 and 1 inversions and rare mutations (denaturing high performance liquid chromatography, conformation sensitive gel electrophoresis) and/or direct sequencing. F8 mutations were identified in 874 (89%), 146 (89%),...
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