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Tissue Engineering

Research reports on tissue engineering from E. Pamula and colleagues provide new insights

Published in Blood Weekly, June 19th, 2008

"Poly(L-lactide-co-glycolide) (PLGA) was synthesized using a biocompatible initiator, zirconium acetylacetonate. In vitro and in vivo degradation properties of PLGA films (produced by solvent casting, 180 mu m thick) and PLGA scaffolds (produced by an innovated solvent casting and particulate leaching, 3 mm thick) were evaluated," scientists writing in the Journal of Materials Science - Materials in Medicine report.

"The samples were either submitted for degradation in phosphate buffered saline (PBS) at 37 degrees C for 30 weeks, or implanted into rat skeletal muscles for 1, 4, 12, 22 and 30 weeks. The degradation was monitored by scanning electron microscopy,...

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