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Celgene Corporation

Data from Studies of Amrubicin in Small-Cell Lung Cancer Presented at the 2008 American Society of Clinical Oncology Meeting Demonstrate Single Agent Anti-Tumor Activity in Western Patient Population

Published in Blood Weekly, June 19th, 2008

Celgene Corporation (Nasdaq:CELG) announced physicians from leading medical centers presented data from two Phase II clinical studies of amrubicin in patients with extensive-disease small-cell lung cancer (SCLC) either sensitive to platinum-based first-line therapy or refractory to platinum-based first-line therapy. Results of the studies demonstrated improved overall response rates that compare favorably with topotecan, as well as no evidence of anthracycline-induced cardiotoxicity with cumulative dosing up to 1,000 mg of amrubicin.

In the first study, a randomized, multi-center U.S. study involving 48 centers, patients with SCLC and sensitive to previous first-line...

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