Biopsy
Research on biopsy published by F.B. Smith et al
Published in Blood Weekly, June 26th, 2008
"Plasma cells are readily identified microscopically after immunostaining for the CD138 antigen, and CD138-stained bone marrow core biopsy sections have proved superior to Giemsa-stained aspirate smears and hematoxylin-eosin (H&E) sections for determining plasma cell percentages in marrow. The CD138-stained plasma cell percentage is generally obtained by visual estimation, after viewing the entire section," investigators in the United States report.
"We propose an alternative method, in which the microscopist initially views the immunostained section under low- and medium-power magnification, then selects a single high-power field in which the relative concentration of...
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Source: Blood Weekly (2008-06-26)
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