Published in Blood Weekly, June 26th, 2008
"Therefore, results from carrier screening and prenatal diagnosis frequently need to be available rapidly. A rapid technique for diagnosis of alpha-thalassemia-1 SEA type was implemented. The technique used is based on real-time gap-PCR and high resolution melting (HRM) analysis of the amplified fragment using the Rotor-Gene 6000 (TM). The DNA samples used for amplification were obtained from whole blood, cord blood, and chorionic...
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