Thrombocytopenia

Research reports from G. Spectre and co-authors provide new insights into thrombocytopenia

Published in Blood Weekly, June 26th, 2008

"Patients with myeloproliferative disorders (MPD) are prone to develop thrombotic complications and thus frequently receive heparin. Surprisingly heparin-induced thrombocytopenia (HIT) has been rarely reported in MPD and is potentially under-diagnosed due to the relatively high platelet count," investigators in Jerusalem, Israel report.

"We report three patients with MPD who developed HIT; all presented with a relative fall of platelet counts (although without an absolute thrombocytopenia), thrombosis or skin necrosis and a positive test for HIT antibodies (particle gel immunoassay). Risk factors for developing HIT in our patients were exposure to unfractionated...

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Source: Blood Weekly (2008-06-26)

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