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Bone Marrow

Kitasato University, Department of Hematology describes research in bone marrow

Published in Blood Weekly, June 26th, 2008

Research findings, 'Accumulation of allo-MHC cross-reactive memory T cells in bone marrow,' are discussed in a new report. According to recent research from Sagamihara, Japan, "The T cells in the bone marrow (BM) have recently been shown to be enriched with memory T cells. We investigated in this study the reactivity of minor-antigen specific memory cytotoxic T lymphocytes (CTLs) induced from the BM of in vivo primed mice using two different antigen systems."

"The antigen-specific CTLs could be efficiently induced from the BM of immunized mice. This CTL activity was not observed with naïve control mice, indicating that the activity was largely attributable to the memory...

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