Immunology
New immunology research has been reported by scientists at Biomedical Primate Research Center
Published in Blood Weekly, June 26th, 2008
New investigation results, 'Oligodendrocyte-specific protein is encephalitogenic in rhesus macaques and induces specific demyelination of the optic nerve,' are detailed in a study published in European Journal of Immunology. "Oligodendrocyte-specific protein (OSP) is a candidate autoantigen in the development of multiple sclerosis (MS). We evaluated the potential of OSP to induce EAE in rhesus monkeys, an out bred animal model for MS that is immunologically close to humans," scientists in Rijswijk, Netherlands report.
"Since OSP is a four-membrane spanning protein with highly hydrophobic regions, we synthesized recombinant proteins encompassing only the...
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Source: Blood Weekly (2008-06-26)
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