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Gene Therapy

Reports outline gene therapy study findings from International Center for Genetic Engineering and Biotechnology

Published in Blood Weekly, July 10th, 2008

Scientists discuss in 'Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice' new findings in gene therapy. "Experimental and clinical evidence indicate that bone marrow cells participate in the process of new blood vessel formation. However, the molecular mechanisms underlying their recruitment and their exact role are still elusive," researchers in Trieste, Italy report.

"Here, we show that bone marrow cells are recruited to the sites of neoangiogenesis through the neuropilin-1 (NP-1) receptor and that they are essential for the maturation of the activated endothelium and the formation of...

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