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Breast Cancer

Research from F.C. Bidard and co-authors yields new data on breast cancer

Published in Blood Weekly, July 24th, 2008

According to recent research published in the journal Clinical Cancer Research, "Clinical significance of disseminated tumor cells (DTC) in bone marrow of early breast cancer patients has been reported, but improvements in detection methods are needed. Bone marrow aspirates from 621 patients with stage I to III breast cancer were screened for cytokeratin-positive (CK+) cells."

"CK+ cells were categorized into DTC only if they had specific morphologic features of tumor cells. Bone marrow status and clinical and pathologic variables of the patients were correlated with clinical outcome after a median follow-up of 56 months. DTC and non-DTC CK+ cells were detected...

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