Proteomics
Researchers at Technical University of Munich target proteomics
Published in Blood Weekly, July 31st, 2008
"This study compared the effects of the human 70-kDa stress protein (Hsp70) peptide, TKDNNLLGRFELSG (TKD), proinflammatory cytokines, or a combination of both on the repertoire of receptors expressed by human natural killer (NK) cells and their capacity to kill human CX colon carcinoma cells, K562 erythroleukemic cells, and leukemic blasts from two patients with acute myelogenous leukemia. Low-dose interleukin (IL) 2/IL-15 and TKD increase the expression density of activatory (NKG2D, NKp30, NKp44, NKp46, CD94/NKG2C) and inhibitory (CD94/NKG2A) receptors on NK cells," researchers in Munich, Germany report.
"Concomitantly, IL-2/TKD treatment enhances the cytotoxicity of...
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Source: Blood Weekly (2008-07-31)
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