Graft-Versus-Host Disease

Reports by P.J. Martin and co-researchers describe recent advances in graft-versus-host disease

Published in Blood Weekly, August 7th, 2008

According to a study from the United States, "The design of clinical trials for prevention or treatment of acute or chronic graft-versus-host disease poses many challenges. These challenges include the selection of primary and secondary endpoints that demonstrate clinical benefit, and the identification of measures indicating success both for individual patients and groups."

"Assessment of response in treatment trials should ideally encompass the prior trajectory of change before treatment. The criteria, timing and duration of response should be specified, and the potential effects of concomitant treatment and complications other than GVHD should be taken into account...

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Source: Blood Weekly (2008-08-07)

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