Tissue Engineering

Research on tissue engineering reported by scientists at Tohoku University

Published in Blood Weekly, August 7th, 2008

"A bone defect that is not repaired with bone completely is designated a non-union defect or a critical-size defect. The biological mechanism that regulates the process of bone repair of the critical-size defect remains unknown," researchers in Sendai, Japan report.

"The present study was designed to investigate bone repair in a critical-size defect compared with that in a smaller or non-critical-size defect. Our original standardized rat calvarial bone defect model was used for the experiment. The rate of bone formation was examined with X-ray morphometry and the bone production of osteoblasts and osteocytes was assessed by molecular histology with in situ...

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Source: Blood Weekly (2008-08-07)

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