Autoimmune Disease

Research on autoimmune disease published by scientists at University of Basel

Published in Blood Weekly, August 7th, 2008

"Many of the clinical, histological and serological manifestations of chronic graft-versus-host disease (GVHD) resemble autoimmune disease (AD), and although the differences are significant, they may be more semantic than biological. Indeed, studies suggest that some ADs may represent a fetal-versus-maternal chronic GVHD," investigators in Basel, Switzerland report.

"Both conditions involve dysregulated immune responses resulting in tissue inflammation, damage, scarring and organ dysfunction, and both may be associated with a genetic predisposition. Epitope-specific autoaggressive phenomena such as immune thrombocytopenic purpura (ITP) are often seen following...

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Source: Blood Weekly (2008-08-07)

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