Published in Blood Weekly, August 14th, 2008
"Some cases respond to the in vitro cross-linking of surface immumoglobulin (sig) with effective activation. In contrast, the remaining cases do not respond to such stimulation, thereby resembling B cells anergized after antigen encounter in vivo," wrote M. Muzio and colleagues, Vita-Salute University.
The researchers concluded: "However the biochemical differences between the 2 groups are ill defined, and in humans the term B-cell anergy lacks a molecular...
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