Thrombophilia

Research reports on thrombophilia from M. Ozbek and colleagues provide new insights

Published in Blood Weekly, August 14th, 2008

According to recent research from Turkey, "Klinefelter syndrome (KS) is the most common sex chromosome disorder in men. It may be associated with an increased risk for venous thrombosis and thromboembolism, which is partially explained by hypofibrinolysis due to androgen deficiency."

"Additional genetic or acquired thrombophilic states have been shown in KS patients complicated with venous thrombosis as isolated case reports. Arterial thrombotic events had not been previously reported in KS. In this study, a young man with KS who developed acute arterial thrombosis during testosterone replacement therapy is presented," wrote M. Ozbek and colleagues.

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Source: Blood Weekly (2008-08-14)

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