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Tissue Engineering

Research from University of Turin has provided new data on tissue engineering

Published in Blood Weekly, August 14th, 2008

According to recent research from Turin, Italy, "A novel, efficient, and rapid synthesis of the 6-aminoperhydro-1,4-diazepine scaffold is reported. It was promoted by microwave or sequential ultrasound/microwave irradiation under solvent-free conditions or in solution."

"Protected ethylenediamine derivatives and N-Boc-serinol dimesylate underwent rapid cyclization to give 6-aminoperhydro-1,4-diazepine derivatives in excellent yields and with high selectivity, whereas the same reaction failed or gave negligible yields under conventional heating. Cesium or potassium ions catalyzed the ring closure by coordinating the sulfonamide groups. All relevant work reported to date...

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