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Myeloma Therapy

New findings reported from B. Burington and co-authors describe advances in myeloma therapy

Published in Blood Weekly, August 21st, 2008

Investigators publish new data in the report 'Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma.' "Changes in global gene expression patterns in tumor cells following in vivo therapy may vary by treatment and provide added or synergistic prognostic power over pretherapy gene expression profiles (GEP). This molecular readout of drug-cell interaction may also point to mechanisms of action/resistance," researchers in the United States report.

"In newly diagnosed patients with multiple myeloma (MM), microarray data were obtained on tumor cells prior to and 48 hours after in...

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