Tissue Engineering
Studies from Sankyo Co., Ltd. have provided new information about tissue engineering
Published in Blood Weekly, September 4th, 2008
Research findings, 'Gene expression profiles in the articular cartilage of juvenile rats receiving the quinolone antibacterial agent ofloxacin,' are discussed in a new report. According to recent research from Tokyo, Japan, "Quinolone antibacterial agents are extensively utilized in antimicrobial chemotherapy. However, they have been reported to induce arthropathy in juvenile animals, and the mechanism has not been clarified."
"In the present study, to investigate the molecular details of the chondrotoxicity of the quinolone ofloxacin (OFLX), it was orally administered by gavage at a dose level of 900 mg/kg once to male juvenile Sprague-Dawley rats, 3 weeks of age. Then...
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Source: Blood Weekly (2008-09-04)
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