Biomedicine
Reports from University of Bergen, Department of Biomedicine advance knowledge in biomedicine
Published in Blood Weekly, October 16th, 2008
Research findings, 'Two distinct tumor phenotypes isolated from glioblastomas show different MRS characteristics,' are discussed in a new report. "We have developed a human brain tumor model in immunodeficient rats that gradually changes its phenotype by serial passages in vivo, from a highly infiltrative, non-angiogenic one with numerous stem cell markers [low-generation (LG) tumor] to a more typical glioblastoma one with extensive angiogenesis and necrosis [high-generation (HG) tumor]. In this study we determined the metabolic properties of these two phenotypes, using (1)H MRS," scientists in Bergen, Norway report.
"The LG tumors showed an intact blood-brain barrier...
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Source: Blood Weekly (2008-10-16)
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