Chronic Myelomonocytic Leukemia

Studies from University of Basel have provided new data on chronic myelomonocytic leukemia

Published in Blood Weekly, October 30th, 2008

"In the absence of a cytogenetic abnormality or overt dysplasia, chronic myelomonocytic leukemia (CMML) may be difficult to be distinguished from reactive monocytosis. We have previously described a typical growth pattern in CMML patients, i.e., 'pseudonormal' colonies resembling granulocytic colonies but consisting entirely of monocytic cells when stained," researchers in Basel, Switzerland report.

"To study the utility of the colony forming unit cell assay (CFU-C) as a diagnostic tool in patients with monocytosis, we analyzed a cohort of 48 consecutive patients referred to our institution with peripheral blood monocytosis. Thirty-six patients fulfilled the WHO...

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Source: Blood Weekly (2008-10-30)

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