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Insulin Resistance

Research from Groningen University broadens understanding of insulin resistance

Published in Blood Weekly, November 6th, 2008

According to recent research from Netherlands, "Insulin resistance has been implicated to underlie both excess cardiovascular disease and chronic transplant dysfunction after renal transplantation. Skeletal muscle mainly determines peripheral insulin resistance, and could therefore affect outcome."

"All transplant recipients at our outpatient clinic with a functioning graft more than 1 year were invited to participate between 2001 and 2003. Mortality and death censored graft loss were recorded until August 2007. We used 24 hr urine creatinine excretion as measure of muscle mass. Cox regression was used to analyze the prospective data. Six hundred four renal transplant...

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