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Hypertension Therapy

Data on hypertension therapy published by researchers at University of Glasgow, Institute of Biomedical Science

Published in Blood Weekly, November 13th, 2008

A new study, 'Pulmonary hypertension: therapeutic targets within the serotonin system,' is now available. According to a study from Scotland, "Pulmonary arterial hypertension (PAH) is characterized by a sustained and progressive elevation in pulmonary arterial pressure and pulmonary vascular remodelling leading to right heart failure and death. Prognosis is poor and novel therapeutic approaches are needed."

"The serotonin hypothesis of PAH originated in the 1960s after an outbreak of the disease was reported among patients taking the anorexigenic drugs aminorex and fenfluramine. These are indirect serotonergic agonists and serotonin transporter substrates. Since then...

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