Scripps Research Institute

Scripps research scientists identify compounds for stem-cell production from adult cells

Published in Blood Weekly, November 20th, 2008

In the study, the scientists screened known drugs and identified small molecules that could replace conventional reprogramming genes, which can have dangerous side effects. This new process offers a new way to generate stem cells from fibroblasts, a general cell type that is abundant and easily accessible from various tissues, including skin.

The study was published in the November 6, 2008 edition (Volume 3, Issue 5) of the journal Cell Stem Cell.

"Our study shows for the first time that somatic or general cell types can be reprogrammed with only two genes and small molecules, and that these small molecules can replace one of the two most essential...

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Source: Blood Weekly (2008-11-20)

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