Ischemia

Study results from National Taiwan University broaden understanding of ischemia

Published in Blood Weekly, November 20th, 2008

"Remote Pulmonary injuries after hepatic reperfusion are frequently caused by reactive oxygen species (ROS)-induced damage. The choice of anesthetics may affect the balance between oxidants and antioxidants, and propofol, a commonly used anesthetic, has an antioxidant effect," investigators in Taipei, Taiwan report.

"In this study, we developed a model to study pulmonary function with hepatic ischemia/reperfusion (I/R) manipulation, with the aim of defining remote Pulmonary dysfunction after hepatic reperfusion and determining if propofol affects this dysfunction by altering ROS production from the liver or lungs. Adult male rats weighing 160-250 g were randomly divided...

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Source: Blood Weekly (2008-11-20)

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