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Study findings from C.S. Sun et al provide new insights into life sciences

Published in Blood Weekly, November 20th, 2008

"The link of proto-oncogenic protein Wnt-1 production with NF-kappa B activation has been functionally demonstrated in PC12 cells, a rat pheochromocytoma cell line of neural crest lineage, while it is not yet verified in human cells. The link can be indirectly supported in our previous report that functional proteomics identifies enhanced expression of NF-kappa B-associated Wnt-1 production in human hepatocellular carcinoma tissues," scientists writing in the Journal of Biomedical Science report.

"This study aimed to further validate this link in human cells using anti-sense strategy. The effects of sequence-specific anti-sense morpholino oligonucleotides (ONs)...

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