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Katholieke University Leuven publishes research in life sciences

Published in Blood Weekly, November 20th, 2008

A new study, 'Development of a liquid chromatography method for the analysis of josamycin,' is now available. According to a study from Leuven, Belgium, "Out of three methods for the analysis of josamycin, the best one was selected and used as starting point for further development. A central composite design was applied to find the most influencing parameters and to optimize the chromatographic conditions and a full factorial design was used to perform a robustness study."

"The final method uses a Hypersil ODS column 5microm, 250mmx4.6mm i.d. maintained at 45 degrees C. The mobile phase is composed of acetonitrile-phosphate buffer (pH 3, 0.2moll(-1))-tetrabutylammonium...

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