Stem Cell Research
Research on stem cell research described by A. Gerbitz and colleagues
Published in Blood Weekly, November 27th, 2008
According to recent research from Berlin, Germany, "Aside from major and minor histocompatibility antigens, genetic polymorphisms of various donor and host genes have been found to be risk factors for graft-yersus-host disease and transplantation-related mortality (TRM). The heme oxygenase I (HO-I) protein has been implicated in regulating inflammatory response and has been described as a ''protective gene'' in solid organ transplantation."
"In humans, the promoter region displays length polymorphism due to a variable number of GT repeats. Individuals exhibiting 29 or fewer GT repeats express higher levels of HO-I on cellular stress compared with individuals with 30 or...
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Source: Blood Weekly (2008-11-27)
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