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Heart Attack

Phase II Trial of Experimental Anti-Coagulant Reports Safety and Outcomes Data

Published in Blood Weekly, November 27th, 2008

Researchers reported on a study of a new oral anti-clotting agent -- rivaroxaban -- designed to identify doses that would be safe to test in subsequent Phase III efficacy and safety trials. The results of ATLAS ACS-TIMI 46 were presented as a late-breaking clinical trial at the American Heart Association's Scientific Sessions 2008.

"The goal of any early study is to find the right dose and the right way to give the drug, and we met that objective," said C. Michael Gibson, M.S., M.D., principal investigator, chief of clinical research at the Beth Israel Deaconess Medical Center and director of the Thrombolysis in Myocardial Infarction (TIMI) data coordinating center at...

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