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Chronic Lymphocytic Leukemia

Research from University of Washington has provided new information about chronic lymphocytic leukemia

Published in Blood Weekly, December 4th, 2008

" We reported encouraging early results of allogeneic hematopoietic cell transplantation (HCT) after nonmyeloablative conditioning in 64 patients who had advanced chronic lymphocytic leukemia (CLL). Here, we have extended the follow-up to a median of 5 years and have included data on an additional 18 patients," investigators in the United States report.

"Patients and Methods Eighty-two patients, age 42 to 72 years, who had fludarabine-refractory CLL were conditioned with 2 Gy total-body irradiation alone or combined with fludarabine followed by HCT from related (n = 52) or unrelated (n = 30) donors. Complete remission (CR) and partial remission were achieved in 55% and...

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