Lymphoma
Research from C.M. Magro and co-authors yields new data on lymphoma
Published in Blood Weekly, December 4th, 2008
"Cutaneous lymphocyte-associated antigen (CLA) is expressed in resident cutaneous T lymphocytes, high endothelial venules, peripheral monocytes, granulocytes and a small percentage of memory B cells. It has been postulated to be an important factor in homing of lymphocytes to the skin because of its function as a ligand for E-selectin expressed on cutaneous endothelial cells," investigators in the United States report.
"We investigated the expression of CLA using the HECA-452 antibody on paraffin-embedded, formalin-fixed tissue in a variety of reactive, neoplastic and preneoplastic cutaneous lymphoid infiltrates of T- and B-cell derivation. CLA was expressed at high...
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Source: Blood Weekly (2008-12-04)
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