American Society of Nephrology

Diabetes drug shows potential for treating one cause of chronic kidney disease

Published in Blood Weekly, December 25th, 2008

The antidiabetes drug rosiglitazone may have the potential to protect kidney function in patients with a condition called focal segmental glomerulosclerosis (FSGS), according to a study appearing in the January 2009 issue of the Clinical Journal of the American Society Nephrology (CJASN). The phase I clinical findings indicate that the drug warrants further study in phase II and phase III trials.

Patients with FSGS—a condition that affects kidney function by attacking the glomeruli units within the kidney that filter blood—have limited treatment options. These individuals develop scarred or hardened blood vessels within the kidney, making the organ inefficient at...

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Source: Blood Weekly (2008-12-25)

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